转载,出处不详,仅供参考学习。
英文 | 中文意义 | 例子 |
常见试剂/仪器 | ||
flask | 烧瓶 | 500 mL 4-neck flask |
separator fenne, | 分液漏斗 | |
vessel | 釜,容器 | |
Grubbs’ II | 一种卡宾配体催化剂,用于烯烃复分解反应 | |
PTC | Phase transfer catalyst | |
SST | 标准史朗克技术,即一套保证无水无氧的标准操作的集合。 | |
solution | 溶液 | The solution/suspension/mixture/slurry was stirred at r.t. for 8 hours. |
suspension | 悬浊液 | |
mixture | 混合物 | |
slurry | 浆状物 | |
r.t. | 室温 (room temperature) | |
solvent | 溶剂 | |
TLC | 薄层层析色谱(thin layer chromagotahty) | The reaction was detected by TLC (EA:PE = 1:4). Product Rf = 0.4, material Rf = 0.6. |
syringe | 注射器 | |
addition fennel | 滴液漏斗 | |
cannula | 钢桥,双针头导管(转移大量丁基锂、格氏试剂时尽量使用) | The Grignard reagent was transferred to an addition fennel via cannula. |
ice bath | 冰浴 | |
0il bath | 油浴 | |
water bath | 水浴 | |
thermometer | 温度计 | |
condenser | 冷凝管 | |
lipase | (脂肪)酶,一般用于酯的水解和醇的酰化的动力学拆分 | |
concentrated, conc. | 浓的 | Conc. HCl |
basin | 树脂,一般用来过反相柱 | |
bleach | 漂白粉溶液,次氯酸钠溶液 | |
one pot | 一锅(反应),即多组分或者多步反应在一个容器进行 | |
tandem | 连串(反应),与上者的区别是前一个反应的中间体必须参与后一个反应 | |
microwave | 微波 | The flask was irradiated in the microwave/UV for 4 hours. |
UV | 紫外线 | |
ultrasonic | 超声 | The nano tube was well dispersed by untrasonic. |
Tube, sealed tube | 试管,封管 | |
反应阶段常见操作(因为描述时为被动时态,所有单词均以这一时态列出) | ||
in situ | 原位,即不分离直接使用 | The ylide was generated in situ and used directly for the addition without isolation. |
isolation | 分离 | |
isolated | 分离的(收率) | 98% yield (GC), 95% yield(isolated). |
allowed | 使,让 | The temperature was allowed to rise to r.t. |
charged | 充满,加入 | |
bubbled | 通入气体(一般需要液面下鼓泡) | Carbon dioxide was bubbled to the premade Grignard reagent. |
attched | 安装,附加(仪器) | A gas absorption device was attched to the flask. |
added | 添加物料 | The MsCl was added dropwise via a springe in 30 minutes. |
in portions | 分次加入 | |
in one portion | 一次加入 | |
dropwise | 滴加 | |
degassed | 脱气,脱去溶剂中残存的空气 | The methanol was degassed then added to the flask. |
refluxed | 回流 | The mixture was refluxed for 4 hours. |
replaced/purged | 置换(一般用于气体) | The flask was replaced/purged with nitrogen. |
cooled/chilled | 冷却 | The solution was cooled under ice bath. |
heated | 加热 | The mixture was heated to 50℃. |
dissolved | 溶解 | |
diluted | 稀释 | |
dispersion | 分散 | NaH (1.0 g, 60% dispersion in mineral oil) |
vigorously | 强烈的(搅拌、震荡) | |
Dean-Stark trap | 分水器 | The solution was coevaportated/ azeotroped with benzene/ethanol to remove water by Dean-Stark trap. |
azeotrope,azeotropic | 共沸,共沸的 | |
coevaporated | 共沸 | |
hydrogenated | 氢化 | To the methanol solution of A was added a catalytic amount of 20% Pd/C(1.0 g, contains 60% water), the suspension was hydrogenated under 1 atm H2 until no gas absorption is observed. |
absorb | 吸收 | |
catalytic | 催化的 | |
sticky | 粘稠的 | (the reaction mixture is sticky and high exothermic, so vigorous stirring is needed.) |
exothermic | 放热的 | |
recovered | 回收的 | |
buffer | 缓冲溶液 | |
analog | 类似物,同系物 | |
后处理阶段常见词汇 | ||
poured | 倾入 | The suspension was quenched with 1 mL 1N HCl, then carefully poured to cold water, shaken and partitioned between 150 mL of DCM and water. The aqueous layer was extracted with DCM (50 mL*3). The combined organic layer was dried over anhydrous Na2SO4. |
shaken | 振荡,摇晃 | |
quenched | 淬灭 | |
partitioned | 分液 | |
extracted | 萃取 | |
organic layer | 有机相 | |
aqueous layer | 水相 | |
dried | 干燥 | |
anhydrous | 无水的 | |
Evaporated | 蒸发(多使用旋转蒸发仪) | The solution was evaporated/ concentrated under reduced pressure. |
concentrated | 浓缩 (多使用旋转蒸发仪) | |
triturated | 磨碎,打浆 | The solid was triturated with DCM and filtered. |
removed | 除去 | The solvent was removed then *** |
discarded | 丢弃,弃去 | The aqueous layer was discarded. |
distilled | 蒸馏 | The residue was distilled under vacuum to obtain 30 g colorless liquid,56% yield, 98.6% purity(GC),bp 90-92 ℃/ 5mmHg. |
residue | 残留物 | |
vacuum reduced pressure | 真空,减压 | |
liquid | 液体 | |
oil | 油,油状物 | |
yield | 收率 | |
purity | 纯度 | |
solidfied | 固化 | The oil was solidified on standing. |
over night | 过夜 | |
hyophilization | 冻干(利用冰的升华干燥,用于对加热极为敏感的化合物) | The isolated enzyme was dried by hyophilization to give a crystal. |
precipitate | 析出,析出物 | Solid was precipitated while cooling. |
dried under vacuum | 真空干燥 | |
conversion | 转化率 | The coversion/ purity was determined with GC/ HPLC. RT(material): 5.34 min; RT(product):6.78 min. |
obtain/ afford | 获得 | |
GC | 气相色谱 | |
HPLC | 高效液相色谱 | |
selectivity | 选择性 | |
GC-MS | 气相色谱-质谱联用 | Main by-products/ impurities was determined by GC-MS/ LC-MS, MS (ESI): 246.5([M+H]+). The suggested structure is ********. |
LC-MS | 液相色谱-质谱联用 | |
by-product | 副产物 | |
impurity | 杂质 | |
chromatography flash chromatography | 层析 快速柱层析(即用气流吹) | The residue was purified by column chromatography on silica gel with ethyl acetate/petroleum ether (1:1) as eluent to give the product. |
eluent | 淋洗剂,洗脱剂 | |
silica | 硅胶 | |
brine | 食盐水 | The organic layer was washed with saturated sodium bicarbonate and brine. |
saturated | 饱和的 | |
foam | 泡沫 | The residue was purified to afford a light yellow foam/ solid/ powder/ crystal, mp 122-126 ℃. |
solid | 固体 | |
crystal | 晶体 | |
powder | 粉末 | |
celite | 硅藻土 | The suspension was carefully poured into cold water. The pH was adjusted to <3 with 1N HCl. Then filtered through celite pad, the cake was washed with DCM. The filtrate was separated.. |
adjusted | 调整(pH值) | |
filtered | 过滤 | |
Filtrate | 滤液 | |
cake | 滤饼,滤渣 | |
acidified | 酸化 | |
basified | 碱化 | |
neutralized | 中和 | |
recrystallized recrystallization | 重结晶(多采用混合溶剂,先加良溶剂加热溶解,后加入不良溶剂到刚刚析出固体,再反加少许良溶剂) | The solid was recrystallized from methol/water (1:1) to afford 3.0 g colorless crystal. The product was purified by recrystallization from methol/water (1:1). |
decompose | 分解 | |
sublimation | 升华 | |
determined | 测定 | |
crude | 粗(产品) | |
Prep-HPLC | 制备液相色谱 | |
Prep-TLC | 制备薄层色谱(刮板) | |
Single crystal | 单晶(常见制备方法为缓慢挥发溶剂法、不良溶剂扩散法等) | |
产品理化数据收集阶段 | ||
1H NMR | 核磁共振氢谱,请注意标准格式。s单峰,d双重,t三重,q四重,m多重。 | 1H NMR(400 MHz, CDCl3) δ1.10 (s, 3H), 1.56 (d, J = 3.6 Hz, 2H), 1.84(dd, J = 3.6 and 4.4 Hz, 1H), 2.16-2.43(m, 2H). |
13C NMR | 核磁共振碳谱,请注意400 M仪器上碳谱是100 MHz。 | 13C NMR(100 MHz, CDCl3) δ17.4, 20.4, 25.7, 58.4, 102.9. |
HRMS | 高分辨率质谱 | HRMS(EI) calcd. For C12H18O(M+): 178.1356, found: 178.1458. |
Anal. | 元素分析 | Anal. Calcd for ****: C 74.02, H 18.54. Found:C 73.98, H 18.50. |
ee | Enantiomeric excess,对映体过量值 | 计算方法: (major – minor)/(major+minor),以百分数表示。 |
de | 非对映异构体过量值 | |
ratio | 比例 | |
er | 对映体比例 | |
dr | 非对映体比例 | |
ORP | 比旋光度(optical rotary power) | αd[20] +10.3 (c 1.0, CH2Cl2) d代表钠灯d线,20代表温度,c代表浓度,1.0即10 mg/ 1mL,后面是溶剂。 需要用测得的值除以当时的浓度换算。 |
UV | 紫外-(可见)光谱 | |
IR | 红外光谱 | |
XRD | X射线衍射,一般用来测定晶体结构 |